I was attempting to license HL7 Soup and Integration Host on a hospital network, but I was getting an error preventing the license number from activating.
The problem was that the calls went through a proxy server.
The solution was to open the .config file for each app and uncomment the section that tells the proxy server to use the default credentials.
<system.net>
<defaultProxy useDefaultCredentials="true">
</defaultProxy>
</system.net>
This isn't credentials for calling the server, just the proxy server.